Pop Smoke, an up and coming rapper, was shot and killed Wednesday morning in what appears to be a home invasion robbery … TMZ has learned.

The rapper was at a home in the Hollywood Hills at around 4:30 AM when 2 men wearing hoodies and masks broke into a house … this according to law enforcement sources. We’re told the 2 men fired multiple shots, striking and critically wounding Pop Smoke. The men were seen fleeing on foot.

Pop Smoke was rushed by ambulance to Cedars-Sinai Medical Center in West Hollywood where he was pronounced dead.

The suspects have not been caught and as far as we know they have not been identified. It’s unclear if Pop Smoke knew the shooters. One man was placed in handcuffs but cops determined he was not involved and was released.

Pop Smoke released an album back in July and one of the songs, “Welcome to the Party,” blew up … it was considered by many the song of the summer. Nicki Minaj did a remix of the song a few months later. He also did a song, “Gatti,” with Travis Scott.

6:56 AM PT — The home is owned by Teddi Mellencamp’s husband, Edwin Arroyave, who owns several homes in Los Angeles. It’s possible Pop Smoke was renting the property.

7:08 AM PT — Nicki Minaj just posted a cryptic message … “The Bible tells us that jealousy is as cruel as the grave. Unbelievable. Rest in Peace, Pop.” By using the term “jealousy,” she seems to be saying there’s a connection between the killers and Pop Smoke. We have not heard this from our law enforcement sources.

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